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NDA: New Drug Application An NDA is made by the sponsor of the new drug who obtains and provides enough evidence of the drug's safety and effectiveness to meet the FDA's requirements for marketing approval

Moisture retention: Glutathione aids in preserving skin moisture, which may contribute to a more hydrated and plum skin texture, which is essential for maintaining a healthy complexion

The plant extract was done in an ice-cold buffer containing 50 mM phosphate buffer (pH 6.5) containing 0.1% triton X, 0.2 mM EDTA, 1% (W/V) polyvinylpyrrolidone (PVP), 1% leupeptine, 0.1% DTT, 1 mM proteinase K, 5 mM ascorbate and centrifuged at 10,000 g at 4 C for 20 min